Lagos Spinsters is a situational comedy series that delves into the chaotic and dramatic lives of three young women, Beatrice, Aisha, and Nancy, living in Lagos' high-end Lekki neighborhood. Relationships, betrayal, secrets, and humor dominate their interactions, with Beatrice's wealthy background setting the tone. Romantic entanglements, like Nancy's with Beatrice's twin brother Kelvin, lead to conflicts, while scandals, including leaked nudes and affairs, shake their friendships. As new characters like Veronica emerge, hidden truths surface, culminating in a cliffhanger proposal that sets the stage for more drama in the next season.